From I-5 take the La Jolla Village Drive exit and go west. At the first major intersection, turn right onto Villa La Jolla Drive. Follow this road up the hill and park in lot P406 (this is a large parking structure). Exit the west side of the building and follow Russell Lane until it intersects Lyman Lane. SERF is at the intersection of Russell and Lyman Lane (building 930 on the map below).
MapLink is a useful campus map that allows you to find not only campus buildings but also relevant services like parking, restaurants, and shuttle stops, for both campus and the Hillcrest Medical Center. Direction to CVRR can be found using the search function on MapLink, or by clicking here.